So, does the chronic MAKE you stupid or PREVENT the stupids???

Correspondent:: HellPope Huey
Date: Thu, 24 Feb 2005 04:55:49 GMT

--------

I'll vote on the side of "prevents," just because its the kind of guy I
AM: A defender of SCIENCE!!!

Marijuana-like Ingredient Could Slow Alzheimer's

Wed Feb 23, 5:02 PM ET

By Janice Billingsley
HealthDay Reporter

WEDNESDAY, Feb. 23 (HealthDay News) -- By suppressing inflammation in
the brain, a synthetic marijuana compound could potentially offer some
protection against Alzheimer's disease (news - web sites), Spanish
scientists report.

The researchers, who studied the brain tissue of deceased Alzheimer's
patients, discovered that many of these patients lose the function of
important cannabinoid brain receptors, which seem to guard against
cognitive decline.

They further discovered in a rat study involving synthetic marijuana
that when these brain receptors were working, they reduced the brain
inflammation that is associated with Alzheimer's.

"This is the first time the effects of such damage have been found in
Alzheimer's patients," said study co-author Maria de Ceballos, head of
the neurodegeneration group at the Cajal Institute, Spain's largest
neuroscience research center, in Madrid. "Previously, it has been known
only in those with acute brain damage from trauma."

The findings appear in the Feb. 23 issue of The Journal of Neuroscience.

The researchers studied cannabinoid receptors called CB1 and CB2, which
are proteins that bind with cannabinoids, the active ingredients of
marijuana. The synergy between these receptors and cannabinoids are
known to provide protective effects against inflammation in the brain.

In the first part of their study, they compared the brain tissue of
deceased Alzheimer's patients to similar tissue from healthy people who
had died at the same age. Those who suffered from Alzheimer's had
significantly reduced functioning of their cannabinoid receptors
compared to the healthy group, which meant those with the disease had
lost the capacity to experience the protective effects of cannabinoids.

Then, in a series of rat experiments, the scientists found cannabinoids
reduced inflammation in the brain and prevented cognitive decline.

To find this, the researchers injected amyloid, a protein that
activates immune cells and leads to cognitive decline, into the brains
of one group of rats. Another group of rats received injections of a
control protein. A third group of rats were injected with cannabinoids
along with amyloid, and a last group received cannabinoids with the
control protein.

After two months, the researchers trained the rats over five days to
find a platform hidden underwater. Rats treated with the control protein
-- with or without the cannabinoids -- and those treated with the
amyloid protein and the cannabinoids were able to find the platform. The
rats treated with the amyloid protein alone did not learn how to find
the platform.

The scientists further confirmed that the amyloid protein activated the
rats' brains' immune cells, causing inflammation, but that the
cannabinoids counteracted this effect and reduced the inflammation.

de Ceballos said the findings suggest that those who are known to be at
risk for Alzheimer's could benefit from using cannabinoids to slow the
progression of the disease.

But she added that much work remains to be done before this can be put
to clinical use.

Alzheimer's experts also warned this is very preliminary work because
it only studied tissue in animals to find the beneficial effects of the
cannabinoids, and, as such, is far from an endorsement of marijuana use
in preventing Alzheimer's.

"The paper doesn't reflect any thought that people should use marijuana
as any kind of therapeutic agent for Alzheimer's. It would be
irresponsible to suggest that," said William Thies, vice president of
medical and scientific affairs for the Alzheimer's Association.

By looking at a new possible agent that could be useful in moderating
the pathology of Alzheimer's, he said, the study joins others examining
the possible ways that the disease advances, including the effects of
cholesterol, inflammation and the presence of amyloid proteins.

"Certainly every one of these papers that gives us new possibilities to
explore is welcome," he said.

Information about the amyloid protein that is a part of Alzheimer's
disease can be found at The National Institute of Aging.

--

HellPope Huey
If I whacked my forehead and went "D'OH!"
for every mistake I'd made,
I could rest a beer can in the hollow

I have never made but one prayer to God,
a very short one:
"O Lord, make my enemies ridiculous."
And God granted it.
- Voltaire

I may be a living legend,
but that sure don't help
when I've got to change a flat tire.
- Roy Orbison

Correspondent:: "ŤBONEHEAD>>"
Date: Thu, 24 Feb 2005 16:10:56 GMT

--------

"HellPope Huey" wrote in message
news:Grinningbastard-30AE0C.22570923022005@news1.west.earthlink.net...
>
> I'll vote on the side of "prevents," just because its the kind of guy I
> AM: A defender of SCIENCE!!!
>

I was always of the mind that LSD could open up some of
the rotten neural passages in Alzhiemer's patients...
Figure if it don't work, at least they can have a little fun....

--

"I have no special talent. I am only passionately curious." Albert Einstein

Correspondent:: HellPope Huey
Date: Thu, 24 Feb 2005 18:07:14 GMT

--------
In article ,
"ŤBONEHEAD>>" wrote:
> "HellPope Huey" wrote in message
> news:Grinningbastard-30AE0C.22570923022005@news1.west.earthlink.net...
> >
> > I'll vote on the side of "prevents," just because its the kind of guy I
> > AM: A defender of SCIENCE!!!
> >
>
>
> I was always of the mind that LSD could open up some of
> the rotten neural passages in Alzhiemer's patients...
> Figure if it don't work, at least they can have a little fun....

Not if someone keeps coming up behind them and whispering "I think that
orderly is really Satan!"

--

HellPope Huey
Composer, Decomposer,
Poseur, EpiscoPopopalian

"The Edge... there is no honest way to explain it
because the only people who really know where it is
are the ones who have gone over."
- Hunter S. Thompson

"I dreamed I went to Heaven,
but they realized it wasn't my time,
so they sent me back to a brewery."
- "Family Guy"

Correspondent:: usenet69@hotmail.com
Date: 24 Feb 2005 16:11:31 -0800

--------
I think we would all agree that there are some people out there who
ABUSE marijuana. It can make people stupid.

I'd also like to add that just becuase somethings helps with a disease
(in very low doses) does not mean that it is good for you in very high
doses.

Correspondent:: DrPostman
Date: Fri, 25 Feb 2005 03:09:54 GMT

--------
On 24 Feb 2005 16:11:31 -0800, usenet69@hotmail.com in accordance with
The Prophecy scribed:

>I think we would all agree that there are some people out there who
>ABUSE marijuana. It can make people stupid.
>
>I'd also like to add that just becuase somethings helps with a disease
>(in very low doses) does not mean that it is good for you in very high
>doses.

I never abused it. I smoked the living shit out of it.

--
DrPostman USPS, MBMC, BsD; "Disgruntled, But Unarmed"
Member,Board of Directors, afa-b, SKEP-TI-CULTŽ #15-51506-253.
AFA-B Official Pollster & Hammer of Thor winner - August 2004
You can email me at: DrPostman(at)gmail.com

"Fart for freedom, fart for liberty, and fart proudly."
-Benjamin Franklin

Correspondent:: usenet69@hotmail.com
Date: 24 Feb 2005 16:11:37 -0800

Correspondent:: "Rev Chain Smerker"
Date: Fri, 25 Feb 2005 00:26:49 GMT

--------

>
> --------------------------------------------
> www.urine-pimp.com
> * pass your urine test *
>

You have a nice lil buisness there, great work!

Correspondent:: DrPostman
Date: Fri, 25 Feb 2005 03:10:56 GMT

--------
On 24 Feb 2005 16:11:37 -0800, usenet69@hotmail.com in accordance with
The Prophecy scribed:

>I think we would all agree that there are some people out there who
>ABUSE marijuana. It can make people stupid.
>
>I'd also like to add that just becuase somethings helps with a disease
>(in very low doses) does not mean that it is good for you in very high
>doses.

Yea, better to have the nausea and lack of appetite if you are dying.

Wouldn't want to die less painfully, eh?

--
DrPostman USPS, MBMC, BsD; "Disgruntled, But Unarmed"
Member,Board of Directors, afa-b, SKEP-TI-CULTŽ #15-51506-253.
AFA-B Official Pollster & Hammer of Thor winner - August 2004
You can email me at: DrPostman(at)gmail.com

"Fart for freedom, fart for liberty, and fart proudly."
-Benjamin Franklin

Correspondent:: "Clave"
Date: Thu, 24 Feb 2005 20:28:13 -0800

--------
"DrPostman" wrote in message
news:j06t119841j0g5njfe0v0hm7nukrf4bnmb@4ax.com...
> On 24 Feb 2005 16:11:37 -0800, usenet69@hotmail.com in accordance with
> The Prophecy scribed:
>
>>I think we would all agree that there are some people out there who
>>ABUSE marijuana. It can make people stupid.
>>
>>I'd also like to add that just becuase somethings helps with a disease
>>(in very low doses) does not mean that it is good for you in very high
>>doses.
>
>
> Yea, better to have the nausea and lack of appetite if you are dying.
>
> Wouldn't want to die less painfully, eh?

The best friend I had at the time died a few years back from colon cancer that
eventually spread throughout his whole abdomen. He was hospitalized and
scheduled for surgery on Christmas Eve. The surgeon wanted to just close him up
when she discovered how shot through he was, but was overruled by his
oncologist. She cut out huge parts of near every organ in his chest.

Well, his body of course didn't work too well after that, and with the chemo and
radiation, he just stopped eating and kind of wasted away. He would spend
*hours* sitting in his bathtub with the shower pelting his back with scalding
hot water, just to make the pain bearable. Anyone who's had migraines or
clusters knows what that's about.

Toward the end, I convinced him to at least *try* pot to quell the nausea. He
procured from a friend, and smoked up one afternoon. We met a little later, and
for the first time in months, he said he felt hungry. Not giggling "Reefer
Madness" high, but better than he'd felt in weeks.

We went to a little Mexican place in Belltown (Seattle) and for the last time in
his life, he enjoyed a full meal of real solid food.

I have a *real* hard time imagining that anyone who's watched anything similar
could be on the "Demon Weed" side of the argument.

Jim

Correspondent:: HellPope Huey
Date: Fri, 25 Feb 2005 17:39:45 GMT

--------
In article ,
"Clave" wrote:

> The best friend I had at the time died a few years back from colon cancer
> that eventually spread throughout his whole abdomen. He was hospitalized and
> scheduled for surgery on Christmas Eve. The surgeon wanted to just close him
> up when she discovered how shot through he was, but was overruled by his
> oncologist. She cut out huge parts of near every organ in his chest.
.........
> Toward the end, I convinced him to at least *try* pot to quell the nausea.
> He procured from a friend, and smoked up one afternoon. We met a little later,
> and for the first time in months, he said he felt hungry. Not giggling "Reefer
> Madness" high, but better than he'd felt in weeks.
> > We went to a little Mexican place in Belltown (Seattle) and for the last time
> in his life, he enjoyed a full meal of real solid food.
> > I have a *real* hard time imagining that anyone who's watched anything
> similar could be on the "Demon Weed" side of the argument.

That story pretty well kicks the ass of hard-liner views that don't
take the flip side into account.... ANY hard-liner views. Yes, there are
a few clear-cut situations in the world, but overall, aste screws you
up; so does inflexibility. The day you say "Well, I could be wrong, or
at least be missing a key point that might modify what I'm saying or
doing" is the day needless clouds begin to part.

"Everything is funny as long as it happens to somebody else."
- Will Rogers

--

HellPope Huey
Trying to shake the snapping cur of Society
offa my pants cuff since 1959

"This will be our reply to violence:
to make music more intensely,
more beautifully,
more devotedly than ever before. "
- Leonard Bernstein

"Magic is the cheat codes for the world.
Sending a signal
to reality's operating system, see?"
- Warren Ellis, "Planetary"

Correspondent:: usenet69@hotmail.com
Date: 2 Mar 2005 13:11:59 -0800

--------

DrPostman wrote:
> On 24 Feb 2005 16:11:37 -0800, usenet69@hotmail.com in accordance
with
> The Prophecy scribed:
>
> >I think we would all agree that there are some people out there who
> >ABUSE marijuana. It can make people stupid.
> >
> >I'd also like to add that just becuase somethings helps with a
disease
> >(in very low doses) does not mean that it is good for you in very
high
> >doses.
>
>
> Yea, better to have the nausea and lack of appetite if you are dying.
>
> Wouldn't want to die less painfully, eh?
>
>
>
>
>

Let me correct myself. This is what I meant to say:

I'd also like to add that just becuase somethings helps with a disease
(in very low doses) does not mean that it is good for a healthy person
in very high doses.

> DrPostman USPS, MBMC, BsD; "Disgruntled, But Unarmed"
> Member,Board of Directors, afa-b, SKEP-TI-CULTŽ #15-51506-253.
> AFA-B Official Pollster & Hammer of Thor winner - August 2004
> You can email me at: DrPostman(at)gmail.com
>
> "Fart for freedom, fart for liberty, and fart proudly."
> -Benjamin Franklin

Correspondent:: DrPostman
Date: Thu, 03 Mar 2005 00:43:22 GMT

--------
On 2 Mar 2005 13:11:59 -0800, usenet69@hotmail.com in accordance with
The Prophecy scribed:

>
>DrPostman wrote:
>> On 24 Feb 2005 16:11:37 -0800, usenet69@hotmail.com in accordance
>with
>> The Prophecy scribed:
>>
>> >I think we would all agree that there are some people out there who
>> >ABUSE marijuana. It can make people stupid.
>> >
>> >I'd also like to add that just becuase somethings helps with a
>disease
>> >(in very low doses) does not mean that it is good for you in very
>high
>> >doses.
>>
>>
>> Yea, better to have the nausea and lack of appetite if you are dying.
>>
>> Wouldn't want to die less painfully, eh?
>>
>>
>>
>>
>>
>
>Let me correct myself. This is what I meant to say:
>
>
>
>I'd also like to add that just becuase somethings helps with a disease
>(in very low doses) does not mean that it is good for a healthy person
>in very high doses.
>

Well of course it isn't. I'm living proof of that. A quarter ounce a
day or more was enough to bring me to my bottom thought. Just
because I can't have it doesn't mean others shouldn't.

--
DrPostman USPS, MBMC, BsD; "Disgruntled, But Unarmed"
Member,Board of Directors, afa-b, SKEP-TI-CULTŽ #15-51506-253.
AFA-B Official Pollster & Hammer of Thor winner - August 2004
You can email me at: DrPostman(at)gmail.com

"Fart for freedom, fart for liberty, and fart proudly."
-Benjamin Franklin

Correspondent:: usenet69@hotmail.com
Date: 2 Mar 2005 13:12:15 -0800

Correspondent:: brthrn@dangermedia.org
Date: 2 Mar 2005 13:22:44 -0800

--------
The only thing that made you ugly is your mother.

Correspondent:: HellPope Huey
Date: Thu, 03 Mar 2005 00:07:42 GMT

--------
In article <1109797935.032896.40110@g14g2000cwa.googlegroups.com>,
usenet69@hotmail.com wrote:

>>I'd also like to add that just because somethings helps with a disease
(in very low doses) does not mean that it is good for a healthy person
in very high doses.

That depends on your definition of a healthy person. I have a case of
glaucoma as big as a pilot whale and I am so mentally ill, I have my own
listing in the DSM-IV. I should have a bong surgically sewn to my left
nipple.

--

HellPope Huey
Yeah, verily, I say unto you,
stomp ye not the flaming fudge bag,
keepeth thy shoes pure.

Humor has as big a fist as any other form
or maybe bigger.
~ James Thurber

"It looks like Bob knows something
the other team doesn't!"
- Enzyte commercial

Correspondent:: "ŤBONEHEAD>>"
Date: Thu, 03 Mar 2005 07:34:52 GMT

--------

"HellPope Huey" wrote in message
news:Grinningbastard-6B35BA.18085602032005@news1.west.earthlink.net...
> In article <1109797935.032896.40110@g14g2000cwa.googlegroups.com>,
> usenet69@hotmail.com wrote:
>
>>>I'd also like to add that just because somethings helps with a disease
> (in very low doses) does not mean that it is good for a healthy person
> in very high doses.
>
> That depends on your definition of a healthy person. I have a case of
> glaucoma as big as a pilot whale and I am so mentally ill, I have my own
> listing in the DSM-IV. I should have a bong surgically sewn to my left
> nipple.

Kinda like this....
http://www.boneheadgrafix.net/breastimplant.jpg

--

"I have no special talent. I am only passionately curious." Albert Einstein

Correspondent:: endus
Date: Thu, 24 Feb 2005 19:59:49 -0500

--------
On Thu, 24 Feb 2005 04:55:49 GMT, HellPope Huey
wrote:

>
> I'll vote on the side of "prevents," just because its the kind of guy I
>AM: A defender of SCIENCE!!!
>
>
>Marijuana-like Ingredient Could Slow Alzheimer's

Now THAT is what I call science. I will be conducting extensive
research on this phenominon in my lab starting tomorrow. Smoke em if
ya got em.
--
endus at the domain endus dot com

Let us visualize the secure man; and by this term, I mean
a man who has settled for financial and personal security
for his goal in life...His ideas and ideals are those of
society in general and he is accepted as a respectable,
but average and prosaic man. But is he a man? Has he
any self-respect or pride in himself? How could he, when
he has risked nothing and gained nothing...How does he feel
when he realizes that he has barely tasted the meal of life;
when he sees the prison he has made for himself in pursuit
of the almighty dollar? If he thinks this is all well and
good, fine, but think of the tragedy of a man who has sacrificed
his freedom on the altar of security, and wishes he could turn
back the hands of time. A man is to be pitied who lacked the
courage to accept the challenge of freedom and depart from the
cushion of security and see life as it is instead of living it
second-hand. - Hunter S. Thompson, The Proud Highway

Correspondent:: DrPostman
Date: Fri, 25 Feb 2005 03:11:37 GMT

--------
On Thu, 24 Feb 2005 19:59:49 -0500, endus in
accordance with The Prophecy scribed:

>On Thu, 24 Feb 2005 04:55:49 GMT, HellPope Huey
> wrote:
>
>>
>> I'll vote on the side of "prevents," just because its the kind of guy I
>>AM: A defender of SCIENCE!!!
>>
>>
>>Marijuana-like Ingredient Could Slow Alzheimer's
>
>Now THAT is what I call science. I will be conducting extensive
>research on this phenominon in my lab starting tomorrow. Smoke em if
>ya got em.

I had to quit about 18 years ago. I wonder if the effects are
long lasting?

--
DrPostman USPS, MBMC, BsD; "Disgruntled, But Unarmed"
Member,Board of Directors, afa-b, SKEP-TI-CULTŽ #15-51506-253.
AFA-B Official Pollster & Hammer of Thor winner - August 2004
You can email me at: DrPostman(at)gmail.com

"Fart for freedom, fart for liberty, and fart proudly."
-Benjamin Franklin