diabetes news
Correspondent:: "nu-monet v7.0"
Date: Tue, 01 Feb 2005 07:36:28 -0700
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http://tinyurl.com/4u4r4
Researchers in Boston have pinpointed a primary
trigger for the most common form of diabetes and
have uncovered evidence that simple, inexpensive
aspirin-like drugs could keep the disease that
affects millions in check.
The researchers, from Joslin Diabetes Center in
Boston, discovered a genetic "master switch" in
the liver that is turned on when people become
obese. Obesity has long been linked to diabetes,
but the reason, until now, has been unknown.
Joslin researchers found that once on, this
switch produces low-level inflammation, which
disrupts the body's ability to process insulin,
causing type 2 diabetes.
But the researchers took the finding one step
further. Reasoning that aspirin-like drugs are
used to quell inflammation, they successfully
used the drugs, called salicylates, to eliminate
the symptoms of type 2 diabetes in mice. Human
tests are already underway in Boston, though no
results have been published.
"These drugs, among the safest drugs known, can
do a surprisingly good job of toning down this
inflammation," said Joslin researcher Dr. Steven
E. Shoelson, lead author of the paper. "These are
hopeful ideas for the future."
Shoelson warned against rushing out to get
salicylates. Their effectiveness has been proved
thus far only in mice...
--
"Money can't buy you happiness,
but when you're poor, you can't
buy shit, and nobody will loan
you happiness."
--nu-monet
Correspondent:: IMBJR
Date: Tue, 01 Feb 2005 19:53:14 +0000
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On Tue, 01 Feb 2005 07:36:28 -0700, in reply to "nu-monet v7.0"
:
>http://tinyurl.com/4u4r4
>
>Researchers in Boston have pinpointed a primary
>trigger for the most common form of diabetes and
>have uncovered evidence that simple, inexpensive
>aspirin-like drugs could keep the disease that
>affects millions in check.
>
>The researchers, from Joslin Diabetes Center in
>Boston, discovered a genetic "master switch" in
>the liver that is turned on when people become
>obese. Obesity has long been linked to diabetes,
>but the reason, until now, has been unknown.
>Joslin researchers found that once on, this
>switch produces low-level inflammation, which
>disrupts the body's ability to process insulin,
>causing type 2 diabetes.
>
>But the researchers took the finding one step
>further. Reasoning that aspirin-like drugs are
>used to quell inflammation, they successfully
>used the drugs, called salicylates, to eliminate
>the symptoms of type 2 diabetes in mice. Human
>tests are already underway in Boston, though no
>results have been published.
>
>"These drugs, among the safest drugs known, can
>do a surprisingly good job of toning down this
>inflammation," said Joslin researcher Dr. Steven
>E. Shoelson, lead author of the paper. "These are
>hopeful ideas for the future."
>
>Shoelson warned against rushing out to get
>salicylates. Their effectiveness has been proved
>thus far only in mice...
I shall to mention this during my due diabetic review.
However, that statement about aspirin being one of the safest drugs
known sounds wrong.